Frequent and complex relapses confound assessment of chloroquine resistance in Cambodian Plasmodium vivax

Chloroquine resistance in Plasmodium vivax.

Plasmodium vivax resistance to chloroquine in Dawei, southern Myanmar.

OBJECTIVE To assess the efficacy of chloroquine in the treatment of Plasmodium vivax malaria in in Dawei District, southern Myanmar. METHODS Enrolled patients at Sonsinphya clinic >6 months of age were assessed clinically and parasitologically every week for 28 days. To differentiate new infections from recrudescence, we genotyped pre- and post-treatment parasitaemia. Blood chloroquine was me...

Confirmed Plasmodium vivax Resistance to Chloroquine in Central Vietnam

Plasmodium vivax resistance to chloroquine (CQ) is currently reported in almost all countries where P. vivax is endemic. In Vietnam, despite a first report on P. vivax resistance to chloroquine published in the early 2000s, P. vivax was still considered sensitive to CQ. Between May 2009 and December 2011, a 2-year cohort study was conducted in central Vietnam to assess the recommended radical c...

RESISTANCE OF PLASMODIUM FALCIPARUM TO CHLOROQUINE IN SOUTH EASTERN IRAN

In vivo and in vitro assessments of the response of P. falciparum to chloroquine using WHO standard kits and techniques were carried out in I ran Shahr, Sistan and Baluchestan province of Iran in 1985. In the in vivo assessment, 24 malaria patients treated with chloroquine (25mg/kg over three days) were followed up for one to four weeks. The mean parasite clearance time was 4.3 days and in...

Plasmodium vivax Malaria Relapses after Primaquine Prophylaxis

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 12, No. 11, November 2006 1795 contacts with clandestine gold panners, mainly Brazilian illegal residents. This population, in which malaria incidence is almost impossible to evaluate, comes from Amapa State, where the incidence of malaria is increasing (5). In 2003, 60.9% of patients with malaria cases at Cayenne Hospital had a Brazilian na...